What is Escitalopram?
Escitalopram is an antidepressant belonging to the inhibitor class. It is used for a variety of psychiatric disorders such as depression, anxiety, fear of open spaces, and the like.
How to use Escitalopram?
Escitalopram is used to treat:
- Acute depression
- Panic attacks; fear of open space
- Panic attacks when in a crowded place
- Obsessive-compulsive disorder
Escitalopram buy can be easily and quickly in our online pharmacy. You can also get advice from a professional pharmacist on possible side effects and interactions. Buy Escitalopram online, you can after having a prescription from your doctor. Or text our online pharmacist, they can help.
Mechanism of action of Escitalopram
Escitalopram belongs to the group of SSRI drugs. Thus, the effects are based on inhibiting serotonin reuptake into the presynapse. As a result, the concentration of serotonin in the synaptic cleft increases.
Citalopram vs Escitalopram
Both drugs are among the most selective in the class of SSRIs. They have no significant affinity for muscarinic, dopaminergic, or noradrenaline receptors.
Citalopram is a mixture of two stereoisomers: R-citalopram and S-citalopram. The stereoisomers are compounds that have the same chemical formula but differ only in the arrangement of the atoms. Escitalopram contains only one isomer, S-citalopram.
Escitalopram has a half-life of 30 hours after multiple 30 hours, and its antidepressant effect usually develops 2-4 weeks after starting treatment.
Citalopram has a half-life of 35 hours. The effect is also seen after 2-4 weeks of treatment, sometimes sooner.
Both of these medications are used to treat anxiety disorders, depression, and other conditions. They are prescription medications approved by your doctor.
The daily single dose of escitalopram is 10 mg per day.
Administration for a variety of disorders:
- Depression. Prescribed 10mg per day. Depending on the effect on the body, can be increased to 20mg. The desired result begins to show after 14-28 days, taking usually lasts 6 months to consolidate the results achieved.
- Panic disorder without fear of open space syndrome. The treatment can be taken at 5 mg per day, increasing to 10 mg over 7 days. The expected result appears after 3 months and the treatment lasts several months.
- Social, generalized and obsessive-compulsive anxiety disorders. 10 mg per day for a long time under supervision and coordination with the doctor.
Best time to take Escitalopram 10 mg
You can take the drug at any time convenient for you, but every day at the same time.
Escitalopram 10 mg: side effects
Side effects occur mostly within 14 days, gradually subsiding. Usually unwanted manifestations are in the form of:
- loss or increase of appetite;
- weight gain;
- unusual dreams;
- decreased sex drive or failure to achieve orgasm in women;
Escitalopram 10 mg should not be used if:
- Hypersensitivity to the active substance.
- Treatment with non-selective irreversible inhibitors and reversible inhibitors because of the possibility of serotonin syndrome.
- Congenital or observed prolonged QT syndrome.
- Use of drugs that cause prolongation of the QT interval
Escitalopram should be used with extreme caution during pregnancy and only after consultation with a physician.
Escitalopram is presumed be excreted with breast milk. Therefore, it is not advisable to breastfeed during therapy.
Although Escitalopram has not been shown to impair cognitive function and psychomotor function, any psychotropic medication may impair judgment and dexterity. Patients should be advised of the potential risk of impaired ability to drive and other mechanical means.
The following medications should not be used with Escitaloprám:
- Irreversible nonselective MAO inhibitors.
- Reversible selective MAOA inhibitors (moclobemide).
- Reversible nonselective MAOIs (linezolid).
- Irreversible selective MAO-B inhibitors (selegiline).
- Drugs that prolong the QT interval.
- The following combinations require precautions:
- Serotonergic drugs (e.g., tramadol, sumatriptan, and other triptans); serotonin syndrome is possible.
Drugs that cause hypokalemia/hypomagnesemia - increased risk of malignant arrhythmias.
Many of the interactions were not listed in this article, so any use of this drug requires consultation with your doctor.
If any adverse reactions occur, seek medical attention immediately. It is also important to follow the dosage according to the instructions or recommended by the doctor, you should not exceed the dose, as this can lead to overdose and adverse reactions.read more