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Neurontin: Instructions for use

Neurontin belongs to the group of drugs intended for the treatment of epilepsy and peripheral neuropathic pain (chronic pain resulting from nerve damage). Gabapentin is the active ingredient of Neurontin.  

Neurontin: Uses

Neurontin is indicated for neuropathic pain in adult patients. Neurontin is also used for monotherapy in the treatment of partial seizures, both with and without secondary generalization. In this case, the drug is used in patients over the age of twelve years.

In children under twelve years of age, Neurontin is used as complex therapy in combination with other drugs for convulsions.

Neurontin: Side effects

Neurontin pill can cause these effects: back and abdominal pain; digestive disorders; headache; stool disorders; cough; dry mouth; peripheral edema; flu-like syndrome; rhinitis; Increased or decreased body weight; otitis media; shortness of breath; pharyngitis; skin rash; gait disturbance; confusion; hyperesthesia; drowsiness. 

In rare cases, dysarthria, asthenia, amblyopia, amnesia, nystagmus, emotional lability, thought disorder, hyperkinesia, acne, pneumonia, diplopia, impaired reflexes, ataxia, insomnia, tremor develop when using Neurontin (Gabapentin). 

In order to prevent side effects, it is important to adhere to your doctor's prescription and follow the instructions. 

Neurontin generic name

Gabapentin is the original drug Neurontin. Generic Neurontin has a similar chemical composition. Gabapentin brand names include Horizant, Graliz, and Neurontin.

Neurontin: Dosage

Neurontin (Gabapentin) is taken orally with plenty of fluid (e.g., a glass of water), regardless of meals. The tablets may be divided in half.

If it is necessary to reduce the dose, cancel the drug or replace it with an alternative remedy, this should be done gradually over at least one week.

For neuropathic pain, it is recommended to start treatment with Neurontin at 900 mg/day. The dose of the drug should be increased to therapeutic for three days. On the first day it is recommended to take Neurontin 300 mg once a day, on the second day - 300 mg 2 times a day, the third day - 3 times a day. Gradually, the dose of the drug is brought to a maximum - of 3.6 g/day.

In partial convulsions, Neurontin monotherapy is carried out from the prescription of the drug at 0.9-3.6 g/day. The drug dose is increased gradually over three days.

Children from 3 to 12 years of age should start treatment with 15 mg/kg/day. The dose is gradually increased to 40 mg/kg/day for children from 3 to 5 years old and to 25-35 mg/kg/day for children over 5 years old.

The interval between applications of Neurontin should be no more than 12 hours. The drug should be withdrawn gradually, reducing the dose over a week.

Neurontin for anxiety

Neurontin 300 is a medicine that is sometimes used for symptoms of anxiety when other treatments have failed. Neurontin (Gabapentin) helps improve sleep because insomnia is a symptom of anxiety.

Neurontin: Drug Class

Neurontin is an anticonvulsant used for seizure disorders and also for some neuropathic pain conditions. It belongs to a separate class of gabapentinoids.

Neurontin and alcohol

Neurontin capsule and alcohol separately cause central nervous system (CNS) depression and respiratory depression. The combination of alcohol and Neurontin (Gabapentin) may worsen one or both effects.

If the victim is not treated for severe alcohol poisoning, he may go into a coma and die. It is necessary to lay the victim on the side, monitor breathing, and call an ambulance.

If the condition with alcohol poisoning is not life-threatening, you can provide first aid at home. It is necessary to flush the stomach with 2-3 liters of liquid (it is better to use boiled water) and give sorbents, such as activated charcoal.

When vomiting occurs, ensure that the victim is in a comfortable position, turn him on his side, and tilt his head, so he does not choke on the vomit.

Does Neurontin help with alcohol withdrawal?

Alcohol dependence is a common disorder. Patients with an alcohol use disorder are at risk of developing alcohol withdrawal syndrome if they stop drinking abruptly. Therefore, doctors prescribe medications such as Neurontin (Gabapentin) or Benzodiazepine and examine the patient every day until alcohol withdrawal symptoms disappear.

Neurontin for nerve pain

In chronic neuropathic pain, the doctor may prescribe Neurontin medication. The patient is experiencing unpleasant, intolerable pain. And in these cases, conventional analgesics do not work, but antiepileptic drugs have proven themselves well.

The duration of intake and withdrawal patterns are determined by the doctor after a thorough examination. Treatment is carried out under the supervision of a neurologist.

Neurontin: Weight gain

Neurontin pill can cause weight gain or loss, depending on the patient's metabolism. The drug can increase appetite or increase cravings for certain foods, such as those high in carbohydrates or fats. Weight gain may be caused by slower metabolism or fluid retention in the body.

How does Neurontin work?

Structurally, Neurontin (Gabapentin) is similar to Gamma - aminobutyric acid, the CNS neurotransmitter. However, in the body, the drug does not bind with the molecules that interact with GABA.

Penetrating into the nervous tissue, the substance blocks the flow of calcium into the cells, resulting in the activation of the inhibitory system and suppression of the excitatory system. The content of serotonin in the blood increases. Pain relief and cessation of seizures occur.

Recreational use of Neurontin leads to a change in a person's consciousness. The surrounding reality changes dramatically, and hallucinations are possible.

The half-life of the active substance in the body is about 5-7 hours. The elimination time does not depend on diet or dosage. It is excreted by the kidneys or by hemodialysis.

Overdose

Uncontrolled administration of the drug Neurontin (Gabapentin) often leads to an overdose. This is a very dangerous condition with direct life-threatening, characterized by the strongest intoxication of the body. 

Signs of overdose: 

• confusion;
• extreme drowsiness;
• slurred speech;
• dizziness;
• double vision;
• lethargy;
• nausea and vomiting;
• diarrhea;
• difficulty breathing;
• coma. 

If symptoms of overdose are detected in a person who has taken Neurontin in an increased dosage or in combination with other toxic substances that intensify the effects of the drug, an ambulance should be called.