Instructions for use of Fluvoxamine
Fluvoxamine (Luvox) is an antidepressant that is prescribed for depressive mental disorders: when the patient almost never enjoys his activities, he feels inner emptiness and is almost constantly in a depressed state of mind.
The action of the active ingredient is based on selective inhibition of serotonin reuptake, the so-called happiness hormone, which releases it through the neurons of the brain. As a result, there is an accumulation of serotonin in the synaptic gap, eliminating its deficiency, which is the cause of depression.
Therapy with this drug corrects depressive mood and reduces anxiety, fear, melancholy, and headaches that often accompany depressive states (the drug has a mild analgesic effect). At the same time, there is almost no significant change in the levels of norepinephrine and dopamine. Fluvoxamine maleate has minimal binding ability to serotonin, histamine, m-cholinoreceptors and adrenoreceptors (α and β).
Fluvoxamine: covid treatment
Although Fluvoxamine is prescribed primarily for patients with depression and anxiety disorders, the drug also helps prevent serious complications of COVID-19.
Serotonin reuptake inhibitors affect sigma-1 receptors, which control the production of cytokines (inflammatory markers) in the brain. This prevents the so-called "cytokine storm": an aggressive immune response to viral infection, which is often fatal in severe cases of COVID-19.
Fluvoxamine also has an antiaggregant effect, successfully preventing the formation of blood clots. During treatment, patients have seen an increase in the plasma levels of melatonin in patients who have taken the drug. Melatonin prevents cytokine storms and lymphopenia in patients with coronavirus.
What is another name for Fluvoxamine?
Fluvoxamine (Luvox) or Luvox is a brand name generic of Fluvoxamine maleate. This drug was developed by Solvay Pharmaceuticals and released to the market in 1994.
It is prescribed to patients with psychiatric disorders characterized by depression of various genes, as well as obsessive thoughts (obsessions), actions (compulsions), or a combination of both.
The use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy, especially in the last trimester, can increase the risk of persistent pulmonary hypertension (PLH) in newborns. Available data show that PLH occurs in about 5 births per 1000 (compared to 1- 2 births per 1000 if the mother did not take SSRIs during the 3rd trimester).
Women of childbearing age are advised to ensure absence during pregnancy and during treatment and to use reliable contraception before starting treatment with this medication.
Prescribing Fluvoxamine Generic to a nursing mother raises the question of interrupting or stopping breastfeeding.
Fluvoxamine and alcohol
Why should Fluvoxamine Generic not be combined with alcohol?
1. Alcohol increases the effects of psychotropic drugs, including Fluvoxamine. Firstly, such symptoms as drowsiness, poor motor skills, poor concentration and slow thinking are concerned. Fluvoxamine inhibits this process, and alcohol enhances this effect.
2. Even a single use of alcohol, negatively affects the biotransformation of drugs, as well as reduces the rate of elimination of drug components by the liver. Therefore, these components are eliminated from the body much more slowly and harmful to the body.
3. Antidepressants that combine alcohol and psychotropic drugs cause excessive depression of the central nervous system. This, in turn, causes very serious and life-threatening side effects. The most serious of these are loss of consciousness, circulatory and respiratory disorders. All of these symptoms pose a direct threat to a person's life.
Fluvoxamine and alcohol should absolutely not be taken at the same time. If the case is severe, malignant neuroleptic syndrome can develop. It depresses the function of the brain, which leads to seizures, deterioration of heart and respiratory function, as well as a blurring of consciousness. All of this can end up being fatal.
This scenario occurs only after consuming a large dose of the drug and a dangerous amount of alcohol.
In order to avoid the consequences of using Fluvoxamine and alcohol together, certain rules must be followed. There should be a time gap between the use of one and the other substance. Fluvoxamine should not be drunk earlier than 48 hours after the last consumption of alcohol. Alcohol should be consumed no earlier than three days after the last Fluvoxamine tablet was drunk.
Treatment: in case of severe intoxication it is necessary to induce vomiting and then take activated charcoal, Enterosgel, Sorbecs, Atoxyl or other sorbents.
If the patient is unconscious, call an ambulance immediately and before the doctor arrives, turn the patient on his side to prevent aspiration of the vomit into the airways.
Fluvoxamine for anxiety
The drug helps to cope with stress, easier to endure traumatic situations and get rid of fears, phobias, and panic attacks without suppressing cognitive function. Fluvoxamine antidepressant helps eliminate sleep problems, frequent awakenings, nighttime insomnia, and daytime sleepiness.
Fluvoxamine Generic is one of the main drugs for the treatment of OCD - antidepressants of the SSRI group. The drug increases serotonin levels in the brain, making the symptoms of OCD less frequent.
The daily dose is 100-200 mg. Gradually, the doctor may increase the dose to 300 mg. The drug can be given in the evening up to 150 mg in a single dose, which is the best time to take Fluvoxamine.
If the daily dose exceeds 150 mg, it is administered in 2-,3 doses. Antidepressants are recommended for 6 months after symptoms of depression have disappeared. In patients with hepatic or renal insufficiency, treatment should be started with a low dose and continued under medical supervision.
Fluvoxamine side effects
Read the instructions before using, as the drug has side effects:
1. Digestive system disorders: Often - accompanied by nausea, sometimes vomiting (usually disappears in the first two weeks of treatment). Constipation, anorexia, dyspepsia, diarrhea, epigastric discomfort, dry mouth, malaise.
2. CNS disorders: drowsiness, dizziness, headache, insomnia, anxiety, psychomotor agitation, restlessness, tremor, restlessness, and asthenia are possible. The patient complains of the occurrence of headache, nausea, dizziness, and restlessness after the abrupt discontinuation of Fluvoxamine.
3. Cardiovascular system: a slight decrease in heart rate (2 to 6 beats per minute), palpitations, and tachycardia may occur.
4. Other: increased sweating, and changes in body weight, may occur.
Some of the above side effects may not be related to Fluvoxamine and may be symptoms of depression.
Fluvoxamine vs Fluoxetine
Fluvoxamine (Luvox) is the drug of first choice for treating obsessive-compulsive disorder (OCD). But Fluvoxamine can cause a number of unpleasant side effects. Fluoxetine (Prozac) is an antidepressant that is good for treating a number of mental illnesses, such as depression and panic disorder.
Indications for Fluoxetine
Fluoxetine is often prescribed to patients with depressive mental states. The remedy is not addictive and does not cause withdrawal syndrome with the following symptoms:
problems with sleep;
obsessive thoughts, fears;
anorexia and bulimia.
Components in Fluoxetine promote serotonin reuptake, which accompanies calmness and self-confidence. These drugs slow down the elimination of neurotransmitters from the body and accelerate their accumulation. For this reason, the patient's condition gradually normalizes. Fluoxetine is recommended for use from 15 days to 2 months until a positive therapeutic effect is obtained. However, it is strictly forbidden to use the drug without a doctor's supervision, because it can lead to complications.
If you use the drug for more than a month, it will be eliminated from the body within 3- 4 weeks. Usually, this period is enough for a person to get used to living in a good mood with a clear mind.
Fluoxetine in the treatment of alcoholism
Fluoxetine is sometimes prescribed when dealing with alcoholism. The positive effect of the drug on the body, along with an increase in serotonin activity, helps alcoholics improve their mood, eliminate symptoms of depression and reduce cravings for alcohol. It should be understood that Fluoxetine can be used to treat alcoholism only if the patient refuses to drink strong drinks and the course of the drug is combined with other methods of treatment such as psychotherapy, narcotic coding, and hypnosis. The dose of Fluoxetine and the duration of treatment can only be determined by a doctor after an initial examination and necessary examinations. This medication is usually prescribed for 90 days or less.
An excessive dosage of the drug causes gastric upset, rapid fatigue, weakness, dizziness, drowsiness, and insomnia. If the recommended dose is significantly exceeded, arrhythmia, arterial hypotension, convulsive muscle spasms, liver dysfunction, and development of hepatic coma may occur. There are known single cases of the lethal outcome as a result of taking doses of the drug in excess of permissible levels. There is no antidote.
Therapeutic measures curating overdose phenomena are gastric lavage, enterosorbent administration, and symptomatic treatment (laxatives with osmotic properties may be used). Methods of detoxification, such as forced diuresis or hemodialysis, are ineffective when the dose of Fluvoxamine maleate is exceeded.
Despite the effectiveness of Fluvoxamine, it has contraindications:
- people with allergies to Fluvoxamine and additional ingredients;
- taking Tizanidine or drugs from the MAO inhibitor series as prescribed by a doctor;
- not prescribed for chronic alcoholics;
- children and adolescents under 18 years of age for the treatment of depression.
Precautions are taken when the patient suffers from:
- have functional disorders of the kidneys or liver;
- is prone to bleeding or seizures.
Caution should also be exercised when prescribing this drug to pregnant and lactating women, persons over 65 years of age. Children between 8 and 18 years of age only receive the medication for obsessive-compulsive disorder and use the minimal doses that give therapeutic effect.
Where can I buy Fluvoxamine?
You can order the drug in our online pharmacy. Fluvoxamine is prescribed only by a doctor, so do not forget to take a prescription for the drug. If you want to get Fluvoxamine over the counter, use the services of our pharmacy. A doctor who works for the pharmacy will write a prescription for Fluvoxamine.read more